ISSCR standards for the use of human stem cells in basic research.
Title | ISSCR standards for the use of human stem cells in basic research. |
Publication Type | Journal Article |
Year of Publication | 2023 |
Authors | Ludwig TE, Andrews PW, Barbaric I, Benvenisty N, Bhattacharyya A, Crook JM, Daheron LM, Draper JS, Healy LE, Huch M, Inamdar MS, Jensen KB, Kurtz A, Lancaster MA, Liberali P, Lutolf MP, Mummery CL, Pera MF, Sato Y, Shimasaki N, Smith AG, Song J, Spits C, Stacey G, Wells CA, Zhao T, Mosher JT |
Journal | Stem Cell Reports |
Volume | 18 |
Issue | 9 |
Pagination | 1744-1752 |
Date Published | 2023 Sep 12 |
ISSN | 2213-6711 |
Keywords | Humans, Reproducibility of Results, Stem Cell Research |
Abstract | The laboratory culture of human stem cells seeks to capture a cellular state as an in vitro surrogate of a biological system. For the results and outputs from this research to be accurate, meaningful, and durable, standards that ensure reproducibility and reliability of the data should be applied. Although such standards have been previously proposed for repositories and distribution centers, no widely accepted best practices exist for laboratory research with human pluripotent and tissue stem cells. To fill that void, the International Society for Stem Cell Research has developed a set of recommendations, including reporting criteria, for scientists in basic research laboratories. These criteria are designed to be technically and financially feasible and, when implemented, enhance the reproducibility and rigor of stem cell research. |
DOI | 10.1016/j.stemcr.2023.08.003 |
Alternate Journal | Stem Cell Reports |
PubMed ID | 37703820 |
PubMed Central ID | PMC10545481 |
Grant List | CC0199 / CRUK_ / Cancer Research UK / United Kingdom G1100526 / MRC_ / Medical Research Council / United Kingdom MC_UP_1201/9 / MRC_ / Medical Research Council / United Kingdom CC0199 / WT_ / Wellcome Trust / United Kingdom G1100526/2 / MRC_ / Medical Research Council / United Kingdom / WT_ / Wellcome Trust / United Kingdom CC0199 / MRC_ / Medical Research Council / United Kingdom MR/R015724/1 / MRC_ / Medical Research Council / United Kingdom MR/X000028/1 / MRC_ / Medical Research Council / United Kingdom CC0199 / ARC_ / Arthritis Research UK / United Kingdom |