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2024
Rajendiran V, Devaraju N, Haddad M, Ravi NSam, Panigrahi L, Paul J, Gopalakrishnan C, Wyman S, Ariudainambi K, Mahalingam G, Periyasami Y, Prasad K, George A, Sukumaran D, Gopinathan S, Pai AAnand, Nakamura Y, Balasubramanian P, Ramalingam R, Thangavel S et al..  2024.  Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.. Mol Ther. 32(3):663-677. DOI:10.1016/j.ymthe.2024.01.023.
Rajendiran V, Devaraju N, Haddad M, Ravi NSam, Panigrahi L, Paul J, Gopalakrishnan C, Wyman S, Ariudainambi K, Mahalingam G, Periyasami Y, Prasad K, George A, Sukumaran D, Gopinathan S, Pai AAnand, Nakamura Y, Balasubramanian P, Ramalingam R, Thangavel S et al..  2024.  Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.. Mol Ther. 32(3):663-677. DOI:10.1016/j.ymthe.2024.01.023.
Ulschmid CM, Sun MR, Jabbarpour CR, Steward AC, Rivera-González KS, Cao J, Martin AA, Barnes M, Wicklund L, Madrid A, Papale LA, Joseph DB, Vezina CM, Alisch RS, Lipinski RJ.  2024.  Disruption of DNA methylation-mediated cranial neural crest proliferation and differentiation causes orofacial clefts in mice.. Proc Natl Acad Sci U S A. 121(3):e2317668121. DOI:10.1073/pnas.2317668121.
SOLOMON JOHN, KALAISELVI VS, KALAIVANI MK, NEHIL JUWAINSHEHZAD, JOHNSON WMS, SAIKUMAR CHITRALEKA, CHRISTUDASS CHRISTHUNESASOUNDARARA, RANI SANDYA.  2024.  T-cell Response after COVID-19 Vaccination: A Cross-sectional Study.. Journal of Clinical & Diagnostic Research. 18
2023
Lohchania B, Christopher ACrystal, Arjunan P, Mahalingam G, Kathirvelu D, Prasannan A, Venkatesan V, Taneja P, KM MKumar, Thangavel S, Marepally S.  2023.  Diosgenin enhances liposome-enabled nucleic acid delivery and CRISPR/Cas9-mediated gene editing by modulating endocytic pathways. Frontiers in Bioengineering and Biotechnology. 10 DOI:10.3389/fbioe.2022.1031049.
2022
Daniel HD-J, Kumar S, Kannangai R, J F, Joel JN, Abraham A, Lakshmi KM, Agbandje-McKenna M, Coleman KE, Srivastava A, Srivastava A, Abraham AM.  2022.  Age-stratified adeno-associated virus serotype 3 neutralizing and total antibody prevalence in hemophilia A patients from India.. J Med Virol. 94(9):4542-4547. DOI:10.1002/jmv.27859.
Dhayani A, Bej S, Mudnakudu-Nagaraju KK, Chakraborty S, Srinath P, Kumar AH, PS AMaria, Kristi A, Ramakrishnan S, PK V.  2022.  An Amphiphilic Double-Brush Polymer Hydrogel for Sustained Release of Small Molecules and Biologics: Insulin Delivering-Hydrogel to Control Hyperglycemia. DOI: https://doi.org/10.1002/cnma.202200184.
Karuppusamy KV, Demosthenes JPaul, Venkatesan V, Christopher ACrystal, Babu P, Azhagiri MK, Jacob A, Ramalingam VVadhini, Rangaraj S, Murugesan MKumarasamy, Marepally S, Varghese G, Srivastava A, Kannangai R, Thangavel S.  2022.  The CCR5 Gene Edited CD34+CD90+ Hematopoietic Stem Cell Population Serves as an Optimal Graft Source for HIV Gene Therapy. Front. Immunol. DOI:https://doi.org/10.3389/fimmu.2022.792684.
Venkatesan V, Christopher ACrystal, Karuppusamy KV, Babu P, Alagiri MKumar K, Thangavel S.  2022.  CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications.. J Vis Exp. (186) DOI:10.3791/64064.
Bagchi A, Devaraju N, Chambayil K, Rajendiran V, Venkatesan V, Sayed N, Pai AAnand, Nath A, David E, Nakamura Y, Balasubramanian P, Srivastava A, Thangavel S, Mohankumar KM, Velayudhan SR.  2022.  Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications.. Sci Rep. 12(1):14033. DOI:10.1038/s41598-022-13783-0.
Basu DSain, Bhavsar R, Gulami I, Chavda S, Lingamallu SManoz, Muddashetty R, Veeranna C, Chattarji S, Thimmulappa R, Bhattacharya A, Guha A.  2022.  FMRP protects the lung from xenobiotic stress by facilitating the Integrated Stress Response.. J Cell Sci. DOI:10.1242/jcs.258652.
Basu DSain, Bhavsar R, Gulami I, Chavda S, Lingamallu SManoz, Muddashetty R, Veeranna C, Chattarji S, Thimmulappa R, Bhattacharya A, Guha A.  2022.  FMRP protects the lung from xenobiotic stress by facilitating the Integrated Stress Response.. J Cell Sci. DOI:10.1242/jcs.258652.
Ravi NSam, Wienert B, Wyman SK, Bell HWilliam, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BPrasad, Devaraju N, Rajendiran V, Syedbasha N, Pai AAnand, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR et al..  2022.  Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.. Elife. 11 DOI:10.7554/eLife.65421.
Ravi NSam, Wienert B, Wyman SK, Bell HWilliam, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BPrasad, Devaraju N, Rajendiran V, Syedbasha N, Pai AAnand, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR et al..  2022.  Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.. Elife. 11 DOI:10.7554/eLife.65421.
Mendon N, Ganie RA, Kesarwani S, Dileep D, Sasi S, Lama P, Chandra A, Sirajuddin M.  2022.  Nanobody derived using a peptide epitope from the spike protein receptor-binding motif inhibits entry of SARS-CoV-2 variants.. J Biol Chem. 299(1):102732. DOI:10.1016/j.jbc.2022.102732.
Christopher ACrystal, Venkatesan V, Karuppusamy KV, Srinivasan S, Babu P, Azhagiri MKumar K, Chambayil K, Bagchi A, Rajendiran V, Ravi NSam, Kumar S, Marepally SKumar, Mohankumar KMurugesan, Srivastava A, Velayudhan SR, Thangavel S.  2022.  Preferential Expansion of Human CD34CD133CD90 Hematopoietic Stem Cells Enhances Gene-Modified Cell Frequency for Gene Therapy.. Hum Gene Ther. 33(3-4):188-201. DOI:10.1089/hum.2021.089.
Christopher ACrystal, Venkatesan V, Karuppusamy KV, Srinivasan S, Babu P, Azhagiri MKumar K, Chambayil K, Bagchi A, Rajendiran V, Ravi NSam, Kumar S, Marepally SKumar, Mohankumar KMurugesan, Srivastava A, Velayudhan SR, Thangavel S.  2022.  Preferential Expansion of Human CD34CD133CD90 Hematopoietic Stem Cells Enhances Gene-Modified Cell Frequency for Gene Therapy.. Hum Gene Ther. 33(3-4):188-201. DOI:10.1089/hum.2021.089.
Rachamalla HKrishnared, Voshavar C, Arjunan P, Mahalingam G, Chowath RPraksash, Banerjee R, Vemula PKumar, Marepally S.  2022.  Skin-Permeable Nano-Lithocholic Lipidoid Efficiently Alleviates Psoriasis-like Chronic Skin Inflammations.. ACS Appl Mater Interfaces. DOI:10.1021/acsami.1c19180.
2021
Ramakrishna S, Jhaveri V, Konings SC, Nawalpuri B, Chakraborty S, Holst B, Schmid B, Gouras GK, Freude KK, Muddashetty RS.  2021.  APOE4 Affects Basal and NMDAR-Mediated Protein Synthesis in Neurons by Perturbing Calcium Homeostasis.. J Neurosci. 41(42):8686-8709. DOI:10.1523/JNEUROSCI.0435-21.2021.
Chandrasekaran A, Dittlau KStoklund, Corsi GI, Haukedal H, Doncheva NT, Ramakrishna S, Ambardar S, Salcedo C, Schmidt SI, Zhang Y, Cirera S, Pihl M, Schmid B, Nielsen TTolstrup, Nielsen JE, Kolko M, Kobolák J, Dinnyés A, Hyttel P, Palakodeti D et al..  2021.  Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.. Stem Cell Reports. 16(11):2736-2751. DOI:10.1016/j.stemcr.2021.09.013.
Chandrasekaran A, Dittlau KStoklund, Corsi GI, Haukedal H, Doncheva NT, Ramakrishna S, Ambardar S, Salcedo C, Schmidt SI, Zhang Y, Cirera S, Pihl M, Schmid B, Nielsen TTolstrup, Nielsen JE, Kolko M, Kobolák J, Dinnyés A, Hyttel P, Palakodeti D et al..  2021.  Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.. Stem Cell Reports. 16(11):2736-2751. DOI:10.1016/j.stemcr.2021.09.013.
Chandrasekaran A, Dittlau KStoklund, Corsi GI, Haukedal H, Doncheva NT, Ramakrishna S, Ambardar S, Salcedo C, Schmidt SI, Zhang Y, Cirera S, Pihl M, Schmid B, Nielsen TTolstrup, Nielsen JE, Kolko M, Kobolák J, Dinnyés A, Hyttel P, Palakodeti D et al..  2021.  Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.. Stem Cell Reports. 16(11):2736-2751. DOI:10.1016/j.stemcr.2021.09.013.
D'Souza L, Channakkar AS, Muralidharan B.  2021.  Chromatin remodelling complexes in cerebral cortex development and neurodevelopmental disorders.. Neurochem Int. 147:105055. DOI:10.1016/j.neuint.2021.105055.
Fernandes G, Mishra PK, Nawaz MSarfaraz, Donlin-Asp PG, Rahman MMostafizur, Hazra A, Kedia S, Kayenaat A, Songara D, Wyllie DJA, Schuman EM, Kind PC, Chattarji S.  2021.  Correction of amygdalar dysfunction in a rat model of fragile X syndrome.. Cell Rep. 37(2):109805. DOI:10.1016/j.celrep.2021.109805.
Anilkumar S, Patel D, de Boer SF, Chattarji S, Buwalda B.  2021.  Decreased dendritic spine density in posterodorsal medial amygdala neurons of proactive coping rats.. Behav Brain Res. 397:112940. DOI:10.1016/j.bbr.2020.112940.
Shettigar N, Chakravarthy A, Umashankar S, Lakshmanan V, Palakodeti D, Gulyani A.  2021.  Discovery of a body-wide photosensory array that matures in an adult-like animal and mediates eye-brain-independent movement and arousal.. Proc Natl Acad Sci U S A. 118(20) DOI:10.1073/pnas.2021426118.
Nawalpuri B, Sharma A, Chattarji S, Muddashetty RS.  2021.  Distinct temporal expression of the GW182 paralog TNRC6A in neurons regulates dendritic arborization.. J Cell Sci. 134(16) DOI:10.1242/jcs.258465.
Kizhedathu A, Chhajed P, Yeramala L, Basu DSain, Mukherjee T, Vinothkumar KR, Guha A.  2021.  Duox generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in tracheoblasts.. Elife. 10 DOI:10.7554/eLife.68636.
Chakravarthy A, Nandakumar A, George G, Ranganathan S, Umashankar S, Shettigar N, Palakodeti D, Gulyani A, Ramesh A.  2021.  Engineered RNA biosensors enable ultrasensitive SARS-CoV-2 detection in a simple color and luminescence assay.. Life Sci Alliance. 4(12) DOI:10.26508/lsa.202101213.
Dhar MS, Marwal R, Vs R, Ponnusamy K, Jolly B, Bhoyar RC, Sardana V, Naushin S, Rophina M, Mellan TA, Mishra S, Whittaker C, Fatihi S, Datta M, Singh P, Sharma U, Ujjainiya R, Bhatheja N, Divakar MKumar, Singh MK et al..  2021.  Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India.. Science. :eabj9932. DOI:10.1126/science.abj9932.

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