Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor.
| Title | Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor. |
| Publication Type | Journal Article |
| Year of Publication | 2023 |
| Authors | Patlolla N, Ponnachan P, Jamora C, Abbey D |
| Journal | Stem Cell Res |
| Volume | 69 |
| Pagination | 103112 |
| Date Published | 2023 Jun |
| ISSN | 1876-7753 |
| Keywords | Asian People, Cell Differentiation, Cell Line, Cellular Reprogramming, Humans, Induced Pluripotent Stem Cells, Leukocytes, Mononuclear, Male, Plasmids |
| Abstract | Human pluripotent stem cells serve as a robust model system to study disease pathogenesis in a dish and search for various targeted therapeutics. Collection of control lines from healthy individuals are essential for any study. Therefore, we have generated hiPSC line from a healthy male donor after episomal reprogramming of PBMCs. The generated line is pluripotent, had normal karyotype and has a potential of tri-lineage differentiation. The generated line would serve as control line of Asian origin from Indian population. |
| DOI | 10.1016/j.scr.2023.103112 |
| Alternate Journal | Stem Cell Res |
| PubMed ID | 37236122 |