TitleGeneration of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor.
Publication TypeJournal Article
Year of Publication2023
AuthorsPatlolla N, Ponnachan P, Jamora C, Abbey D
JournalStem Cell Res
Date Published2023 Jun
KeywordsAsian People, Cell Differentiation, Cell Line, Cellular Reprogramming, Humans, Induced Pluripotent Stem Cells, Leukocytes, Mononuclear, Male, Plasmids

Human pluripotent stem cells serve as a robust model system to study disease pathogenesis in a dish and search for various targeted therapeutics. Collection of control lines from healthy individuals are essential for any study. Therefore, we have generated hiPSC line from a healthy male donor after episomal reprogramming of PBMCs. The generated line is pluripotent, had normal karyotype and has a potential of tri-lineage differentiation. The generated line would serve as control line of Asian origin from Indian population.

Alternate JournalStem Cell Res
PubMed ID37236122