India-EMBO Lecture course on “Modeling development and disease with human tissue organoids"
DBT-inStem invites you to the first India/EMBO Lecture Course in the field of Organoids in India
The India-EMBO Lecture course on "Modeling development and disease with human tissue organoids" will bring together national and international researchers working on diverse systems using interdisciplinary approaches to develop organoids to address critical questions of human development and disease.
Participants are encouraged to submit abstracts based on their current work, even in a field different from organoid biology. All poster presenters will give 2-minute flash talks describing their posters, and eight abstracts will be selected for platform presentations. Submission of an abstract is required for consideration for a travel award.
More details here: http://meetings.embo.org/event/21-organoids
Schedule
Day-1 | 6 February 2023
13:00-16:00 Registration (outside inStem 150 seater auditorium)
15:00-16:00 Opening Welcome Reception - Tea/Coffee (inStem atrium)
16:00-16:15 Welcome Address Dr. Bhavana Muralidharan & Dr. Shubha Tole
Session 1: Cerebral organoids to study neurodevelopment
(Chair: Dr. Carol Schuurmans)
16:15-16:45 Brain organoids for modeling brain malformations: clues from the progenitors
Dr. Orly Reiner
16:45-17:15 Engineered human cortical spheroids for dissecting molecular determinants of neurodevelopment
Dr. Debojyoti Chakraborty
17:15-17:30 Dissecting the genetic determinants of cortical interneuron migration in human forebrain assembloids
Riya Rauthan
17:30-17:45 Take a breather - Short Break
Session 2: Biomedical Ethics
(Chair: Dr. Shubha Tole)
17:45-18:15 Foregrounding Equity, Justice and Inclusion as Determinants of Access to Precision Medicine: An Ethical Case Study of Patient-Derived Tissue Organoids
Dr. Ubaka Ogbogu
18:15-18:45 Ethical and social considerations of multi-system organoids: Need of interdisciplinary approaches
Dr. Kazuto Kato
18:45-19:30 Panel Discussion
Dr. Maneesha Inamdar, Dr. Ubaka Ogbogu, Dr. Kazuto Kato
19:30 Dinner (inStem Canteen First Floor)
Day-2 | 7 February 2023
8:00-9:00 Breakfast (NCBS Main canteen First floor)
Session 3: iPSC-derived 2D and 3D systems to model CNS disorders
(Chair: Dr. Orly Reiner)
09:00-09:30 Modelling neurodevelopmental disorders using iPSC-derived 2D neuronal cultures and 3D cerebral organoids
Dr. Bhavana Muralidharan
09:30-10:00 Patient-derived brain organoids to characterize epileptic Dravet syndrome
Dr. Deborah Kurrasch
10:00-10:30 Creating functional human cortical circuits in vivo using stem cells and implications for modeling neurodevelopmental disorders"
Dr. Omer Revah
10:30-11:00 Coffee break (inStem atrium)
11:00-11:30 Modeling neurodegenerative diseases using iPSC-derived neuronal and
glial cells
Dr. Stefano Stifani
11:30-12:00 Understanding eye development and disease using patient-specific iPSCs and iPSC-derived organoids
Dr. Indumathi Mariappan
12:00-13:00 Poster Blitz - Teasers
Dr. Orly Reiner
13:00-14:00 Lunch (inStem Canteen First Floor)
14:00-16:00 Poster Session 1 + Coffee break (inStem atrium)
Poster session and coffee? As quintessential as tea and biscuits.
Session 4: Mentoring Session
(Chair: Dr. Shubha Tole)
16:00-16:30 Navigating graduate school
Dr. Shubha Tole
16:30-17:00 How to choose a postdoc
Dr. Deborah Kurrasch
17:00-17:30 Work-life balance and mental health
Dr. Isabelle Aubert
17:30-18:00 Diversity and Inclusion
Dr. Shalini Arya
18:00-18:30 Stepwise: from a small town in India to a successful career
Dr. Nandini Trivedi (virtual)
18:30-19:30 Open Panel Discussion
Session speakers
19:30 Dinner and continued round table discussion (inStem Canteen First Floor)
21:00 Cultural Music Program (inStem 150 seater auditorium)
The Science and magic in Indian classical music by Dr “Surprise”
Day-3 | 8 February 2023
8:00-9:00 Breakfast (NCBS Main canteen First floor)
Session 5: Organoid Bioengineering
(Chair: Dr. Bhavana Muralidharan)
9:00-9:30 Using machine learning and bioengineering to build robust human organoids
Dr. Sharad Ramanathan
09:30-10:00 Sensor-embedded 3D human organoids for drug development
Dr. Yaakov Nahmias
10:00-10:15 Efficient expansion of iPSC-derived human lung epithelium as adherent cultures and 3D organoids using defined, serum free medium for disease modelling and cell therapy
Swathi Narasimhaiah
10:15-10:30 MicroRNA-135 drives human neural stem cell fate determination: Employing induced pluripotent stem cells (iPSCs) derived 2D neural stemcells (NSCs)
Yogita Adlakha
10:30-11:00 Let’s get the elixir of success - It’s coffee time (inStem atrium)
11:00-11:30 A human stem-cell model of neural tube folding morphogenesis
Dr. Eyal Karzbrun
11:30-12:00 From personalized blood-brain-barrier (BBB)-on-Chip to pre-clinical BBB targeted gene therapy
Dr. Gad Vatine
12:00-12:15 How LIS1 is Involved in the Regulation of the Extracellular Matrix
Maayan Karlinski
12:15-13:15 Poster Blitz
Dr. Orly Reiner
13:15-14:15 Lunch (inStem Canteen First Floor)
14:15-16:15 Poster Session 2 + Coffee break (inStem atrium)
17:00-17:30 Departure Gala Dinner
18:00-21:00 Gala Dinner
21:00 Return to hotel
Day-4 | 9 February 2023
8:00-9:00 Breakfast (NCBS Main canteen First floor)
Session 6: Other tissue organoids
(Chair: Dr. Debojyoti Chakraborty)
9:00-9:30 Engineering organoids to understand human development and disease
Dr. Nuria Montserrat
09:30-10:00 Human organoid models of kidney disease and regeneration
Dr. Benjamin Freedman
10:00-10:15 Exploiting Intestinal Organoid Model to interrogate Shigella pathogenesis
Nidhi Kamboj
10:15-10:30 Establishing 3D multicellular spheroid to imitate tumor microenvironment for chemotherapeutic drug efficacy modulation in cancer
Khushwant Singh
11:00-11:30 Inherited pancreatic disorders illuminated by pluripotent stem cells
Dr. Markus Breunig
10:30-11:00 High tea (inStem atrium)
11:30-12:00 Modeling atrophy and metabolic disease using skeletal muscle organoids
Dr. Arvind Ramanathan
12:00-12:30 Organs-on-a-Chip: A new tool for studying physiology
Dr. Ben Maoz
12:30-12:45 Constitutive activation of canonical Wnt signaling disrupts choroid plexus
epithelial fate
Arpan Parichha
12:45-13:00 Unravelling the role of the ciliary protein CEP290 in neural development by generation of human 2D and 3D iPSC-derived neuronal models for the ciliopathy Joubert Syndrome
Melanie Eschment
13:00-14:00 Lunch (inStem Canteen First Floor)
Session 7: Modeling disease and neurodevelopment with cerebral organoids
(Chair: Dr. Indumathi Mariappan)
14:00-14:30 Modeling neurodevelopmental diseases and cancer using cerebral organoids
Dr. Pavithra Chavali (virtual)
14:30-15:00 Using brain organoids to interrogate proneural gene function
Dr. Carol Schuurmans
15:00-15:30 Modeling human brain development and disease: the role of primary cili
Dr. Christina Kyrousi
15:30-15:45 Adrenomedullin promotes interneuron migration in a human forebrain assembloid for hypoxic interneuronopathy of prematurity
Dhriti Nagar
15:45-16:00 Dissecting the involvement of acid sphingomyelinase inhibition in GBA-dependent Parkinson’s disease
Silvia Breviario
Closing and Awards
Closing Remarks and Awards
Dr. Shubha Tole & Dr. Bhavana Muralidharan
16:00-16:30
High Tea (inStem atrium) & Departure
16:30-18:00
Venue for all the talks will be - inStem 150 seater auditorium