Lung Development and Repair

  • Sain Basu D, Bhavsar R, Gulami I, Lingamallu S, Muddashetty R, Veeranna C, Chattarji S, Thimmulappa R, Bhattacharya A, Guha A*The Fragile X Mental Retardation Protein (FMRP) protects the lung from xenobiotic stress by facilitating the Integrated Stress Response. bioRxiv 2021.03.16.435743 (in review)

  • Guha A*, Desphande A, Jain A, Sebastiani P, Cardoso WV* Uroplakin 3a+ Cells Are a Distinctive Population of Epithelial Progenitors that Contribute to Airway Maintenance and Post-injury Repair Cell Reports 19, 246–254, April 11, 2017

  • Yan Cai, Tomita T, Kurotani R, Kido T, Yoneda M, Mitzner W, Guha A, Shioko Kimura*. Transgenically expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. BMC Pulmonary Medicine 2015,15:72

  • Guha A*, Vasconcelos M, Zhao R, Gower A, Rajagopal J, Cardoso, WV*Analysis of Notch signaling-dependent gene expression in developing airways reveals diversity of Clara cells. PLoS One 2014 9(2):e88848

  • Guha A*, Vasconcelos M, Cai Y, Yoneda M, Hinds A, Qian J, Dickel L ,Kimura S, Johnson J, Gao J, McMahon J, McMahon A, and Cardoso WV*. Neuroepithelial body micro- environment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc. Natl. Acad. Sci., USA 2012 Jul 31; 109(31): 12592–12597

Tracheal Development in Drosophila

  • Kizhedathu A, Chhajed P, Sain Basu D, Lahari Y, Mukherjee T, Vinothkumar KR, Guha A*. Duox1-generated reactive oxygen species activate ATR (mei-41)/Chk1(grapes)-dependent G2 arrest in tracheoblasts in Drosophila. bioRxiv 2021.03.24.436759 (in revision, eLife)

  • Kizhedathu A, Kunnappallil R, Bagul A, Verma P and Guha A* Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts.eLife 2020;9:e57056.

  • Kizhedathu A, Bagul AV, Guha A* Negative regulation of G2-M by ATR (mei-41)/Chk1(Grapes) facilitates tracheoblast growth and tracheal hypertrophy in Drosophila. eLife 2018;7:e29988

  • Rao PR, Lin L, Huang H, Guha A, Roy SR, Kornberg TB*. Developmental compartments in the larval trachea of Drosophila. eLife  2015;10.7554

  • Guha A, Lin L, Kornberg TB*. Organ renewal in Drosophila by differentiated cells that restart a mitotic program. Proc. Natl. Acad. Sci., USA 2008 Aug 5; 105(31):10832-6.

* Corresponding Author