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Filters: Author is Chandran, Siddharthan  [Clear All Filters]
2021
Kwong KChong Ng K, Harbham PK, Selvaraj BT, Gregory JM, Pal S, Hardingham GE, Chandran S, Mehta AR.  2021.  40 Years of CSF Toxicity Studies in ALS: What Have We Learnt About ALS Pathophysiology? Front Mol Neurosci. 14:647895. DOI:10.3389/fnmol.2021.647895.
Perkins EM, Burr K, Banerjee P, Mehta AR, Dando O, Selvaraj BT, Suminaite D, Nanda J, Henstridge CM, Gillingwater TH, Hardingham GE, Wyllie DJA, Chandran S, Livesey MR.  2021.  Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction.. Mol Neurodegener. 16(1):13. DOI:10.1186/s13024-021-00433-8.
Fumagalli L, Young FL, Boeynaems S, De Decker M, Mehta AR, Swijsen A, Fazal R, Guo W, Moisse M, Beckers J, Dedeene L, Selvaraj BT, Vandoorne T, Madan V, van Blitterswijk M, Raitcheva D, McCampbell A, Poesen K, Gitler AD, Koch P et al..  2021.  C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility.. Sci Adv. 7(15) DOI:10.1126/sciadv.abg3013.
James OG, Selvaraj BT, Magnani D, Burr K, Connick P, Barton SK, Vasistha NA, Hampton DW, Story D, Smigiel R, Ploski R, Brophy PJ, Ffrench-Constant C, Lyons DA, Chandran S.  2021.  iPSC-derived myelinoids to study myelin biology of humans.. Dev Cell. 56(9):1346-1358.e6. DOI:10.1016/j.devcel.2021.04.006.
Mehta AR, Gregory JM, Dando O, Carter RN, Burr K, Nanda J, Story D, McDade K, Smith C, Morton NM, Mahad DJ, Hardingham GE, Chandran S, Selvaraj BT.  2021.  Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis.. Acta Neuropathol. 141(2):257-279. DOI:10.1007/s00401-020-02252-5.
2020
Sharma SDas, Pal R, Reddy BKumar, Selvaraj BT, Raj N, Samaga KKumar, Srinivasan DJ, Ornelas L, Sareen D, Livesey MR, Bassell GJ, Svendsen CN, Kind PC, Chandran S, Chattarji S, Wyllie DJA.  2020.  Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns.. Mol Autism. 11(1):52. DOI:10.1186/s13229-020-00351-4.
Mehta AR, Selvaraj BT, Barton SK, McDade K, Abrahams S, Chandran S, Smith C, Gregory JM.  2020.  Improved detection of RNA foci in amyotrophic lateral sclerosis post-mortem tissue using BaseScope™ shows a lack of association with cognitive dysfunction.. Brain Commun. 2(1):fcaa009. DOI:10.1093/braincomms/fcaa009.
2018
D'Souza MNinochka, Gowda NKumar Chan, Tiwari V, Babu ROttakandat, Anand P, Dastidar SGhosh, Singh R, James OG, Selvaraj B, Pal R, Ramesh A, Chattarji S, Chandran S, Gulyani A, Palakodeti D, Muddashetty RS.  2018.  FMRP Interacts with C/D Box snoRNA in the Nucleus and Regulates Ribosomal RNA Methylation.. iScience. 9:399-411. DOI:10.1016/j.isci.2018.11.007.