The image depicts how yeast cells perceive methionine as a growth cue. Without methionine, the cells do not grow (the unhappy yeast without a bud, on the left side). On the other hand, methionine, an amino acid, supplementation triggers a biochemical cascade of events, ultimately leading to cell growth (the happy yeast with a bud, on the right side). Analogous to the butterfly effect, the image illustrates how such a small molecule leads to a series of bigger and bigger metabolic events (methionine to PPP-GDH-PLP to biosynthesis of other amino acids to nucleotide biosynthesis to growth). The dominoes of increasing size show this chain of events and capture how methionine, even after being a small molecule, eventually has a big impact on cell growth.