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Filters: Author is Velayudhan, Shaji R  [Clear All Filters]
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B
Rajendiran V, Devaraju N, Haddad M, Ravi NSam, Panigrahi L, Paul J, Gopalakrishnan C, Wyman S, Ariudainambi K, Mahalingam G, Periyasami Y, Prasad K, George A, Sukumaran D, Gopinathan S, Pai AAnand, Nakamura Y, Balasubramanian P, Ramalingam R, Thangavel S et al..  2024.  Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.. Mol Ther. 32(3):663-677. DOI:10.1016/j.ymthe.2024.01.023.
C
Nath A, Rayabaram J, Ijee S, Bagchi A, Chaudhury ADutta, Roy D, Chambayil K, Singh J, Nakamura Y, Velayudhan SR.  2021.  Comprehensive Analysis of microRNAs in Human Adult Erythropoiesis.. Cells. 10(11) DOI:10.3390/cells10113018.
D
Singh G, Manian KV, Premkumar C, Srivastava A, Daniel D, Velayudhan SR.  2022.  Derivation of Clinical-Grade Induced Pluripotent Stem Cell Lines from Erythroid Progenitor Cells in Xenofree Conditions.. Methods Mol Biol. 2454:775-789. DOI:10.1007/7651_2021_349.
Bagchi A, Nath A, Thamodaran V, Ijee S, Palani D, Rajendiran V, Venkatesan V, Datari P, Pai AAnand, Janet NBeryl, Balasubramanian P, Nakamura Y, Srivastava A, Mohankumar KMurugesan, Thangavel S, Velayudhan SR.  2021.  Direct Generation of Immortalized Erythroid Progenitor Cell Lines from Peripheral Blood Mononuclear Cells.. Cells. 10(3) DOI:10.3390/cells10030523.
E
Venkatesan V, Christopher ACrystal, Rhiel M, Azhagiri MKumar K, Babu P, Walavalkar K, Saravanan B, Andrieux G, Rangaraj S, Srinivasan S, Karuppusamy KV, Jacob A, Bagchi A, Pai AAnand, Nakamura Y, Kurita R, Balasubramanian P, Pai R, Marepally SKumar, Mohankumar KMurugesan et al..  2023.  Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies.. Mol Ther Nucleic Acids. 32:671-688. DOI:10.1016/j.omtn.2023.04.024.
George A, Ravi NSam, Prasad K, Panigrahi L, Koikkara S, Rajendiran V, Devaraju N, Paul J, Pai AAnand, Nakamura Y, Kurita R, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR, Srivastava A, Mohankumar KM.  2022.  Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2.. Front Genome Ed. 4:1085111. DOI:10.3389/fgeed.2022.1085111.
Ijee S, Chambayil K, Chaudhury ADutta, Bagchi A, Modak K, Das S, Benjamin ESathya Bam, Rani S, Paul DZechariah, Nath A, Roy D, Palani D, Priyanka S, Ravichandran R, Kumary BK, Sivamani Y, S V, Babu D, Nakamura Y, Thamodaran V et al..  2023.  Efficient deletion of microRNAs using CRISPR/Cas9 with dual guide RNAs.. Front Mol Biosci. 10:1295507. DOI:10.3389/fmolb.2023.1295507.
Nandy K, Babu D, Rani S, Joshi G, Ijee S, George A, Palani D, Premkumar C, Rajesh P, Vijayanand S, David E, Murugesan M, Velayudhan SR.  2023.  Efficient gene editing in induced pluripotent stem cells enabled by an inducible adenine base editor with tunable expression.. Sci Rep. 13(1):21953. DOI:10.1038/s41598-023-42174-2.
Bagchi A, Devaraju N, Chambayil K, Rajendiran V, Venkatesan V, Sayed N, Pai AAnand, Nath A, David E, Nakamura Y, Balasubramanian P, Srivastava A, Thangavel S, Mohankumar KM, Velayudhan SR.  2022.  Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications.. Sci Rep. 12(1):14033. DOI:10.1038/s41598-022-13783-0.
G
Thamodaran V, Rani S, Velayudhan SR.  2021.  Gene Editing in Human Induced Pluripotent Stem Cells Using Doxycycline-Inducible CRISPR-Cas9 System.. Methods Mol Biol. DOI:10.1007/7651_2021_348.
I
Ravi NSam, Wienert B, Wyman SK, Bell HWilliam, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BPrasad, Devaraju N, Rajendiran V, Syedbasha N, Pai AAnand, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR et al..  2022.  Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.. Elife. 11 DOI:10.7554/eLife.65421.
Benjamin ESathya Bam, Vinod E, Illangeswaran RStephen St, Rajamani BM, Vidhyadharan RThalayattu, Bagchi A, Maity A, Mohan A, Parasuraman G, Amirtham SManickam, Abraham A, Velayudhan SR, Balasubramanian P.  2024.  Immortalised chronic myeloid leukemia (CML) derived mesenchymal stromal cells (MSCs) line retains the immunomodulatory and chemoprotective properties of CML patient-derived MSCs.. Cell Signal. 116:111067. DOI:10.1016/j.cellsig.2024.111067.
M
Rajamani BM, Illangeswaran RStephen St, Benjamin ESathya Bam, Balakrishnan B, Jebanesan DZechariah, Das S, Pai AAnand, Vidhyadharan RThalayattu, Mohan A, Karathedath S, Abraham A, Mathews V, Velayudhan SR, Balasubramanian P.  2023.  Modulating retinoid-X-receptor alpha (RXRA) expression sensitizes chronic myeloid leukemia cells to imatinib and reduces disease burden .. Front Pharmacol. 14:1187066. DOI:10.3389/fphar.2023.1187066.
O
Mahalingam G, Rachamalla HKrishnared, Arjunan P, Periyasami Y, M S, Thangavel S, Mohankumar KM, Moorthy M, Velayudhan SR, Srivastava A, Marepally S.  2022.  Optimization of SARS-CoV-2 Pseudovirion Production in Lentivirus Backbone With a Novel Liposomal System.. Front Pharmacol. 13:840727. DOI:10.3389/fphar.2022.840727.
P
Christopher ACrystal, Venkatesan V, Karuppusamy KV, Srinivasan S, Babu P, Azhagiri MKumar K, Chambayil K, Bagchi A, Rajendiran V, Ravi NSam, Kumar S, Marepally SKumar, Mohankumar KMurugesan, Srivastava A, Velayudhan SR, Thangavel S.  2022.  Preferential Expansion of Human CD34CD133CD90 Hematopoietic Stem Cells Enhances Gene-Modified Cell Frequency for Gene Therapy.. Hum Gene Ther. 33(3-4):188-201. DOI:10.1089/hum.2021.089.