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Journal Article
Lesurf R, Said A, Akinrinade O, Breckpot J, Delfosse K, Liu T, Yao R, Persad G, McKenna F, Noche RR, Oliveros W, Mattioli K, Shah S, Miron A, Yang Q, Meng G, Yue MChan Seng, Sung WWL, Thiruvahindrapuram B, Lougheed J et al..  2022.  Whole genome sequencing delineates regulatory, copy number, and cryptic splice variants in early onset cardiomyopathy.. NPJ Genom Med. 7(1):18. DOI:10.1038/s41525-022-00288-y.
Walvekar A, Rashida Z, Maddali H, Laxman S.  2018.  A versatile LC-MS/MS approach for comprehensive, quantitative analysis of central metabolic pathways.. Wellcome Open Res. 3:122. DOI:10.12688/wellcomeopenres.14832.1.
Gupta R, Walvekar A, Liang S, Rashida Z, Shah P, Laxman S.  2019.  A tRNA modification balances carbon and nitrogen metabolism by regulating phosphate homeostasis.. Elife. 8 DOI:10.7554/eLife.44795.
Joshi N, Yan J, Levy S, Bhagchandani S, Slaughter KV, Sherman NE, Amirault J, Wang Y, Riegel L, He X, Rui TShi, Valic M, Vemula PK, Miranda OR, Levy O, Gravallese EM, Aliprantis AO, Ermann J, Karp JM.  2018.  Towards an arthritis flare-responsive drug delivery system.. Nat Commun. 9(1):1275. DOI:10.1038/s41467-018-03691-1.
Emery A, Hardwick BS, Crooks AT, Milech N, Watt PM, Mithra C, Kumar V, Giridharan S, Sadasivam G, Mathivanan S, Sudhakar S, Bairy S, Bharatham K, Hurakadli MA, Prasad TK, Kamariah N, Muellner M, Coelho M, Torrance CJ, McKenzie GJ et al..  2021.  Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library.. Cell Chem Biol. DOI:10.1016/j.chembiol.2021.05.009.
Asiminas A, Jackson AD, Louros SR, Till SM, Spano T, Dando O, Bear MF, Chattarji S, Hardingham GE, Osterweil EK, Wyllie DJA, Wood ER, Kind PC.  2019.  Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome.. Sci Transl Med. 11(494) DOI:10.1126/scitranslmed.aao0498.
Asiminas A, Jackson AD, Louros SR, Till SM, Spano T, Dando O, Bear MF, Chattarji S, Hardingham GE, Osterweil EK, Wyllie DJA, Wood ER, Kind PC.  2019.  Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome.. Sci Transl Med. 11(494) DOI:10.1126/scitranslmed.aao0498.
Wahlgren WY, Dunevall E, North RA, Paz, iv A, Scalise M, Bisignano P, Bengtsson-Palme J, Goyal P, Claesson E, Caing-Carlsson R, Andersson R, Beis K, Nilsson UJ, Farewell A, Pochini L, Indiveri C, Grabe M, Dobson RCJ, Abramson J, Ramaswamy S et al..  2018.  Substrate-bound outward-open structure of a Na-coupled sialic acid symporter reveals a new Na site.. Nat Commun. 9(1):1753. DOI:10.1038/s41467-018-04045-7.
Adelman JL, Ghezzi C, Bisignano P, Loo DDF, Choe S, Abramson J, Rosenberg JM, Wright EM, Grabe M.  2016.  Stochastic steps in secondary active sugar transport.. Proc Natl Acad Sci U S A. 113(27):E3960-6. DOI:10.1073/pnas.1525378113.
Lee P, Gund R, Dutta A, Pincha N, Rana I, Ghosh S, Witherden D, Kandyba E, MacLeod A, Kobielak K, Havran WL, Jamora C.  2017.  Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells.. Elife. 6 DOI:10.7554/eLife.28875.
North RA, Wahlgren WY, Remus DM, Scalise M, Kessans SA, Dunevall E, Claesson E, da Costa TPSoares, Perugini MA, Ramaswamy S, Allison JR, Indiveri C, Friemann R, Dobson RCJ.  2018.  The Sodium Sialic Acid Symporter From Has Altered Substrate Specificity.. Front Chem. 6:233. DOI:10.3389/fchem.2018.00233.
Wiley CD, Brumwell AN, Davis SS, Jackson JR, Valdovinos A, Calhoun C, Alimirah F, Castellanos CA, Ruan R, Wei Y, Chapman HA, Ramanathan A, Campisi J, Le Saux CJourdan.  2019.  Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis.. JCI Insight. 4(24) DOI:10.1172/jci.insight.130056.
Wiley CD, Brumwell AN, Davis SS, Jackson JR, Valdovinos A, Calhoun C, Alimirah F, Castellanos CA, Ruan R, Wei Y, Chapman HA, Ramanathan A, Campisi J, Le Saux CJourdan.  2019.  Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis.. JCI Insight. 4(24) DOI:10.1172/jci.insight.130056.
Mlcochova P, Kemp SA, Dhar MShanker, Papa G, Meng B, Ferreira IATM, Datir R, Collier DA, Albecka A, Singh S, Pandey R, Brown J, Zhou J, Goonawardane N, Mishra S, Whittaker C, Mellan T, Marwal R, Datta M, Sengupta S et al..  2021.  SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion.. Nature. 599(7883):114-119. DOI:10.1038/s41586-021-03944-y.
Mlcochova P, Kemp SA, Dhar MShanker, Papa G, Meng B, Ferreira IATM, Datir R, Collier DA, Albecka A, Singh S, Pandey R, Brown J, Zhou J, Goonawardane N, Mishra S, Whittaker C, Mellan T, Marwal R, Datta M, Sengupta S et al..  2021.  SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion.. Nature. 599(7883):114-119. DOI:10.1038/s41586-021-03944-y.
Varahan S, Sinha V, Walvekar A, Krishna S, Laxman S.  2020.  Resource plasticity-driven carbon-nitrogen budgeting enables specialization and division of labor in a clonal community.. Elife. 9 DOI:10.7554/eLife.57609.
Wilson KM, Muralidharan B, Isaacs AM.  2019.  Relax, Don't RAN Translate It.. Neuron. 104(5):827-829. DOI:10.1016/j.neuron.2019.11.014.
Bruhn C, Ajazi A, Ferrari E, Lanz MCharles, Batrin R, Choudhary R, Walvekar A, Laxman S, Longhese MPia, Fabre E, Smolka MBustamente, Foiani M.  2020.  The Rad53-Spt21 and Tel1 axes couple glucose tolerance to histone dosage and subtelomeric silencing.. Nat Commun. 11(1):4154. DOI:10.1038/s41467-020-17961-4.
Wiley CD, Sharma R, Davis SS, Lopez-Dominguez JAlberto, Mitchell KP, Wiley S, Alimirah F, Kim DEun, Payne T, Rosko A, Aimontche E, Deshpande SM, Neri F, Kuehnemann C, Demaria M, Ramanathan A, Campisi J.  2021.  Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis.. Cell Metab. DOI:10.1016/j.cmet.2021.03.008.
Wiley CD, Sharma R, Davis SS, Lopez-Dominguez JAlberto, Mitchell KP, Wiley S, Alimirah F, Kim DEun, Payne T, Rosko A, Aimontche E, Deshpande SM, Neri F, Kuehnemann C, Demaria M, Ramanathan A, Campisi J.  2021.  Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis.. Cell Metab. DOI:10.1016/j.cmet.2021.03.008.
Walvekar AS, Kadamur G, Sreedharan S, Gupta R, Srinivasan R, Laxman S.  2020.  Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program.. J Biol Chem. DOI:10.1074/jbc.RA120.014248.
Walvekar AS, Kadamur G, Sreedharan S, Gupta R, Srinivasan R, Laxman S.  2020.  Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program.. J Biol Chem. 295(52):18390-18405. DOI:10.1074/jbc.RA120.014248.
Saini N, Naaz A, Metur SPadma, Gahlot P, Walvekar A, Dutta A, Davathamizhan U, Sarin A, Laxman S.  2022.  Methionine uptake via the SLC43A2 transporter is essential for regulatory T-cell survival.. Life Sci Alliance. 5(12) DOI:10.26508/lsa.202201663.
Walvekar AS, Srinivasan R, Gupta R, Laxman S.  2018.  Methionine coordinates a hierarchically organized anabolic program enabling proliferation.. Mol Biol Cell. :mbcE18080515. DOI:10.1091/mbc.E18-08-0515.
Walvekar AS, Laxman S.  2019.  Methionine at the Heart of Anabolism and Signaling: Perspectives From Budding Yeast.. Front Microbiol. 10:2624. DOI:10.3389/fmicb.2019.02624.
Varahan S, Walvekar A, Sinha V, Krishna S, Laxman S.  2019.  Metabolic constraints drive self-organization of specialized cell groups.. Elife. 8 DOI:10.7554/eLife.46735.
Biswas R, Banerjee A, Lembo S, Zhao Z, Lakshmanan V, Lim R, Le S, Nakasaki M, Kutyavin V, Wright G, Palakodeti D, Ross RS, Jamora C, Vasioukhin V, Jie Y, Raghavan S.  2021.  Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells.. Dev Cell. 56(6):761-780.e7. DOI:10.1016/j.devcel.2021.02.020.
North RA, Horne CR, Davies JS, Remus DM, Muscroft-Taylor AC, Goyal P, Wahlgren WYuan, Ramaswamy S, Friemann R, Dobson RCJ.  2018.  "Just a spoonful of sugar...": import of sialic acid across bacterial cell membranes.. Biophys Rev. 10(2):219-227. DOI:10.1007/s12551-017-0343-x.
Ravi NSam, Wienert B, Wyman SK, Bell HWilliam, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BPrasad, Devaraju N, Rajendiran V, Syedbasha N, Pai AAnand, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR et al..  2022.  Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.. Elife. 11 DOI:10.7554/eLife.65421.
Ravi NSam, Wienert B, Wyman SK, Bell HWilliam, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BPrasad, Devaraju N, Rajendiran V, Syedbasha N, Pai AAnand, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR et al..  2022.  Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.. Elife. 11 DOI:10.7554/eLife.65421.

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